Biomaterials For Oral And Craniomaxillofacial Applications

The majority of the global population is affected by repair or replacement of craniofacial structures caused by tooth decay or loss as well as major craniofacial defects, necessitating complex tissue augmentation or regeneration procedures. As a result of exciting developments and the increasing number of novel biomaterials and different clinical applications, it is extremely important to understand these biomaterials and their design. This publication integrates the application of biomaterials science and describes the recent advances, the role of cutting-edge biomaterials in engineering oral tissues, surface modification technologies, the emerging field of nanomaterials and clinical translation showing future directions in oral and craniomaxillofacial health care. Researchers active in dental, medical and biomaterials sciences, oral and maxillofacial surgeons, dentists, tissue engineers as well as materials scientists will find valuable information on the latest progress and novel approaches as will all those who are looking for better solutions to the problems associated with facial deformities.

Nanostructured Biomaterials for Cranio-maxillofacial and Oral Applications examines the combined impact of materials science, biomedical and chemical engineering, and biology to provide enhanced biomaterials for applications in maxillo-facial rehabilitation and implantology. With a strong focus on a variety of material classes, it examines material processing and characterization techniques to decrease mechanical and biological failure in the human body. After an introduction to the field, the most commonly used materials for cranio-facial applications, including ceramics, polymers and glass ceramics are presented. The book then looks at nanostructured surfaces, functionally graded biomaterials and the manufacturing of nanostructured materials via 3-D printing. This book is a valuable resource for scientists, researchers and clinicians wishing to broaden their knowledge in this important and developing field. Explores the techniques used to apply nanotechnology to biomaterials for cranio-maxillofacial and oral applications Bridges the gap between fundamental materials science and medicine Shows how nanostructured biomaterials respond when implanted in the human body

Biomaterials for Oral and Dental Tissue Engineering examines the combined impact of materials, advanced techniques and applications of engineered oral tissues. With a strong focus on hard and soft intraoral tissues, the book looks at how biomaterials can be manipulated and engineered to create functional oral tissue for use in restorative dentistry, periodontics, endodontics and prosthodontics. Covering the current knowledge of material production, evaluation, challenges, applications and future trends, this book is a valuable resource for materials scientists and researchers in academia and industry. The first set of chapters reviews a wide range of biomaterial classes for oral tissue engineering. Further topics include material characterization, modification, biocompatibility and biotoxicity. Part Two reviews strategies for biomaterial scaffold design, while chapters in parts three and four review soft and hard tissues. Connects materials science with restorative dentistry Focuses on the unique field of intraoral tissues Highlights long-term biocompatibility and toxicity of biomaterials for engineered oral tissues

This issue of Oral and Maxillofacial Surgery Clinics of North America focuses on Emerging Biomaterials in Oral and Maxillofacial Surgery, and is edited by Dr. Alan Herford. Articles will include: Basic Principles of Bioengineering and Regeneration; Soft Tissue Regeneration Incorporating 3D Biomimetic Scaffolds; Advances in Orofacial Stem Cells for Tissue Regeneration; Tissue Engineering for Vertical Ridge Reconstruction; Integrating Biomaterials in Trauma; Tissue Engineered Pre-vascularized Bone and Soft Tissue Flaps; Application of Biomaterials for Implant Therapy; Maxillofacial Defects and Use of Growth Factors; New Frontiers in Biomaterials; Soft Tissue Engineering; and much more!

Oral tissue engineering involves the study of current approaches for in vitro regeneration of soft and hard tissues located into the oral cavity. In this context, recent approaches involves the use of innovative biomaterials to replace the lost or damaged human oral tissues. Recent discoveries in materials science and nanotechnology are drastically changing the traditional approach to dentistry by the design of innovative devices able more efficiently supporting the natural regeneration process. The objective of this book is to highlight current progress in tissue engineering for various dental hard/soft tissues including enamel, dentin, pulp, alveolar bone, periodontium, gum and oral mucosa, by emphasizing the role of materials and their specific applications.

Ceramics have been used as biomaterials for oral and maxillofacial applications due to their excellent bioactivity, high hardness and wear resistance. One of the key drawbacks of synthetic implants is their failure to adapt to the local tissue environment. Improvements in reliability and biocompatibility of implants and prostheses can be achieved through surface modifications including the use of biomaterial thin films and nanocoatings. This book provides readers with information about dental implants and biomateriual fabrication for maxillofacial procedures and dental bone / tissue repair. It is an ideal reference for medical and dental students and professionals (dentists, oral and maxillofacial surgeons, orthopedic surgeons, prosthodontics) who are involved in implantology and tissue engineering. It will also provide valuable insights into the application and production of bioactive materials for any researchers and apprentices in materials science and biomedical engineering.

This book provides a thorough, up-to-date description of the scientific basis and concepts of tissue engineering in the oral and maxillofacial region. The opening chapters present an introduction to tissue engineering, describe the roles of biomaterials and stem cells, discuss the use of growth factors, and examine potential adverse reactions. The challenges of soft and hard tissue engineering for oral and maxillofacial reconstruction are then considered in detail. It is explained what has been achieved to date, and potential future perspectives are explored. The importance and the verification of adequate vascularization are discussed, and a further focus is the use of 3D printing, both in the planning and production of scaffolds and in the bioprinting of cells and biomaterials. Information is also included on safety, efficacy, and regulatory aspects. Tissue Engineering in Oral and Maxillofacial Surgery will be of interest to all researchers and practitioners who wish to learn more about the potential of tissue engineering to revolutionize practice in oral and maxillofacial surgery.

This new edition reflects the remarkable clinical and scientific advances in bone and soft tissue reconstruction since publication of the first edition of this award-winning book 7 years ago. Highly potent recombinant growth factors are now widely available, and numerous chapters describe and provide cases illustrating how to incorporate these protein therapeutics into clinical practice. The reader will find information about the basic principles of tissue engineering, use of growth factors in orthopedics, and potential applications of gene therapy in dentistry. The book also features chapters on periodontal regeneration and localized implant site development. A section on applications for craniofacial reconstruction describes procedures for use of growth factors in the treatment of defects. The final section addresses orthopedic indications for tissue engineering. An invaluable, up-to-date resource for practitioners wanting to integrate tissue engineering into their clinical practice, researchers seeking inspiration for new directions, and those new to this fascinating field.