Biomedical Optical Sensors

This book provides wide-ranging coverage of current developments in biomedical sensing based on photonic techniques. Biomedical sensing is a dynamic topic that promises to deliver much in the future evolution of medical diagnostics, delivering advanced tools for fundamental research in biology at the micrometre and nanometre scales. The book explores a variety of alternative physical and biological methodologies that have become available for application, such as plasmonic sensors and photonic crystal biosensors. At the same time, it addresses issues that potentially limit the capability of biomedical optical sensing techniques, while reviewing the state-of-the-art in biomedical optical sensing for the future work that will lead to near-universal applications of such techniques. Edited and written by leading experts in this domain, this book is ideal as a comprehensive manual for researchers and graduate students.

This authoritative new resource presents fiber optic sensors and their applications in medical device design and biomedical engineering. Readers gain an understanding of which technology to use and adopt, and how to connect technologies with their respective applications. This book explores the innovation of diagnostics and how to use diagnostic tools. Principles of fiber optic sensing are covered and include details about intensity-based sensors, fiber bragg gratings, distributed sensors, and fabry-perot interferometers. This book explores interrogation software, standards for medical sensors, and discusses protocols and tools for validation. Various medical device engineering and applications are examined, including sensor catheterization, cardiovascular sensors, diagnostic in gastroscopy, urology, neurology, sensing in thermal ablation. Applications and detection of SPR sensors are presented, along with minimally invasive robotic surgery, smart textiles, wearable sensors and fiber-optic spectrometric sensors. This is a one-stop reference on fiber optic sensors for biomed applications.

The field of plasmonics has shown extraordinary capabilities in realizing highly sensitive and accurate sensors for environmental monitoring and measurement of biological analytes. The inherent potential of such devices has led to growing interest worldwide in commercial fiber optic chemical and biosensors. Optical Sensors for Biomedical Diagnostics and Environmental Monitoring is an essential resource for students, established researchers, and industry developers in need of a reference work on both the fundamentals and latest advances in optical fiber sensor technology in biomedical diagnostics and environmental monitoring. The book includes rigorous theory and experimental techniques of surface plasmon and lossy mode resonances, as well as real-time sensing applications of resonance techniques implemented over optical fiber substrate using bulk layer and/or nanostructures as transducer and sensing layers. In addition, discussion of various design options for real-time sensors in environmental monitoring and biomedical diagnostics make the book approachable to readers from multidisciplinary fields.

Optical Fiber Biosensors: Device Platforms, Biorecognition, Applications provides a comprehensive overview of the field of fiber optic sensors using an interdisciplinary approach that covers the fabrication of sensing devices and optical hardware, the functionalization to perform selective biorecognition, and the main applications of biosensors, with a present and a future outlook. Chapters discuss the principles of light propagation and the sensing devices suitable to perform biosensing with optical fibers, the process to functionalize the previous devices to selective biosensing, and applications in cells, small molecules, biomarkers and protein sensing, with a birds eye view on the most important results. This book provides a coherent picture of fiber optic biosensors, from the start (the device) to the end (the application), explaining in simple terms what is the whole process for development of a biosensor. The book also contains practical material (e.g. commercial instruments, fabrication instructions, medical standards for biocompatibility) that cannot be easily found elsewhere, and this is very useful for researchers to plan their development and build their labs. Covers the technologies and operating principles of optical fiber devices used in biosensing Contains chapters on the chemistry and operational strategy to functionalize a fiber device to become an effective biosensor Addresses the main applications of fiber optic biosensors and their specialization

Sensors are the eyes, ears, and more, of the modern engineered product or system- including the living human organism. This authoritative reference work, part of Momentum Press's new Sensors Technology series, edited by noted sensors expert, Dr. Joe Watson, will offer a complete review of all sensors and their associated instrumentation systems now commonly used in modern medicine. Readers will find invaluable data and guidance on a wide variety of sensors used in biomedical applications, from fluid flow sensors, to pressure sensors, to chemical analysis sensors. New developments in biomaterials- based sensors that mimic natural bio-systems will be covered as well. Also featured will be ample references throughout, along with a useful Glossary and symbols list, as well as convenient conversion tables.

While most books contain some information on related sensors topics, they are limited in their scope on biomedical sensors. Sensors in Biomedical Applications: Fundamentals, Design, Technology and Applications is the first systematized book to concentrate on all available and potential sensor devices of biomedical applications! Sensors in Biomedical Applications presents information on sensor types in a comprehensive and easy to understand format. The first four chapters concentrate on the basics, lending an understanding to operation and design principles of sensor elements. Introduced are sections on: basic terms, sensor technologies, sensor structure and sensing effects. The next three chapters describe application possibilities: physical sensors, sensors for measuring chemical qualities and biosensors. Finally, a chapter covers biocompatability, in addition to an appendix and glossary. Sensors in Biomedical Applications is the definitive reference book for a broad audience. All physicists, chemists and biologists interested in the chemical basis and effects of sensors will find this work invaluable. Biomedical engineers and sensor specialists will find the text useful in its pointed analysis of special design, processing and application problems. Physicians practicing with diagnostic tools will want to see the possibilities and limits of biomedical sensors. Finally, students of all of the above areas who wish to learn more about the basics of biomedical sensors need to have this book.

This book describes important recent developments in fiber optic sensor technology and examines established and emerging applications in a broad range of fields and markets, including power engineering, chemical engineering, bioengineering, biomedical engineering, and environmental monitoring. Particular attention is devoted to niche applications where fiber optic sensors are or soon will be able to compete with conventional approaches. Beyond novel methods for the sensing of traditional parameters such as strain, temperature, and pressure, a variety of new ideas and concepts are proposed and explored. The significance of the advent of extended infrared sensors is discussed, and individual chapters focus on sensing at THz frequencies and optical sensing based on photonic crystal structures. Another important topic is the resonances generated when using thin films in conjunction with optical fibers, and the enormous potential of sensors based on lossy mode resonances, surface plasmon resonances, and long-range surface exciton polaritons. Detailed attention is also paid to fiber Bragg grating sensors and multimode interference sensors. Each chapter is written by an acknowledged expert in the subject under discussion.