Borane Reagents

Derived from the renowned, Encyclopedia of Reagents for Organic Synthesis (EROS), the related editors have created a new handbook which focuses on chiral reagents used in asymmetric synthesis and is designed for the chemist at the bench. This new handbook follows the same format as the Encyclopedia, including an introduction and an alphabetical arrangement of the reagents. As chiral reagents are the key for the successful asymmetric synthesis, choosing the right reagents is essential, in this handy reference the editors give details on how to prepare, store and use the reagents as well as providing key reactions to demonstrate where reagents have been successfully used. Comprehensive information on 226 reagents Covers 64 reagents which were not included in EROS All information in one easy to use volume – at an affordable price All reagents included will be added to e-EROS – please visit the site where you can gain access to over 50,000 reactions and 3,800 of the most frequently consulted reagents. Visit: www.interscience.wiley.com/eros

The leading researcher in the uses of boranes in organic synthesis here reviews his work over the past thirty-five years, covering such areas as steric strains, the nonclassical ion problem, selective reductions, hydroboration, and the organoboranes as synthetic intermediates. But more than an exposition of enormous accomplishment, the book is a scientific autobiography that will provide chemists with historical perspective on their profession. The author's detailed narrative of his own research experiences not only adds to the understanding of the present state of the study of boranes, but will serve as a stimulus to imaginative research in the future.

With the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field. This interdisciplinary field has the potential to provide answers to problems and challenges faced in catalysis, synthetic organic chemistry and the development of therapeutic agents and new materials. Providing an invaluable volume, Organometallic Chemistry Volume 41 contains analysed, evaluated and distilled information on the latest in organometallic chemistry research including developments and applications of Lewis acidic boron reagents, masked low-coordinate main group species in synthesis and the diiron centre.

For the first time, the whole field of organoboronic acids is presented in one comprehensive handbook. Professor Dennis Hall, a rising star within the community, covers all aspects of this important substance class, including applications in chemistry, biology and medicine. Starting with an introduction to the structure, properties, and preparation of boronic acid derivatives, together with an overview of their reactions and applications, the book goes on to look at metal-catalyzed borylation of alkanes and arenas, coupling reactions and rhodium-catalyzed additions of boronic acids to alkenes and carbonyl compounds. There follows chapters on copper-promoted C-O and C-N cross-coupling of boronic acids, recent applications in organic synthesis, as well as alpha-haloalkylboronic esters in asymmetric synthesis. Later sections deal with cycloadditions, organoboronic acids, oxazaborolidines as asymmetric inducers, and boronic acid based receptors and sensors. The whole is rounded off with experimental procedures, making this invaluable reading for organic, catalytic and medicinal chemists, as well as those working in organometallics.

Handbook of Reagents for Organic Synthesis Reagents, Auxiliaries and Catalysts for C-C Bond Formation Robert M. Coates and Scott E. Denmark The University of Illinois, Urbana, USA Recognising the critical need for bringing a handy reference work that deals with the most popular reagents in synthesis to the laboratory of practising organic chemists, the Editors, of the acclaimed Encyclopedia of Reagents for Organic Synthesis (EROS) have selected the most important and useful reagents employed in contemporary organic synthesis. The Handbook of Reagents for Organic Synthesis; Reagents Auxiliaries and Catalysts for C-C Bond Formation, provides practical and concise information on a diverse group of reagents. To familiarise the user with the spectrum of reagents contained within this volume, the editors have subdivided more than 200 entries into 22 classes based on their chemical structures and function. The articles, arranged alphabetically, contain all of the information found in EROS as well as expanded reagents listings. In addition, new listings of recently published review articles and monographs are included, as well as relevant Organic Syntheses procedures that deal with either the preparations or reactions of the featured reagents. This comprehensive and well referenced handbook will prove of great value to all practitioners in the field of organic chemistry.

The second supplement to the three volume reference work Comprehensive Asymmetric Catalysis critically reviews new developments to the hottest topics in the field written by recognised experts. Seven chapters which are already in the major reference work have been supplemented and additionally a new chapter on Aminohydroxylation of Carbon-Carbon Double Bonds has been included. Thus, the state of the art in this area is now re-established. Together with the basic three volume book set and Supplement 1 it is not only the principal reference source for synthetic organic chemists, but also for all scientific researchers who use chiral compounds in their work (for example, in biochemical investigations and molecular medicine) as well as for pharmaceutical chemists and other industrial researchers who prepare chiral compounds.

This monograph has been written to demonstrate to organic chemists and graduate students the strategies for controlling stereochemistry in carbon-carbon bond formations with borane intermediates. The boranes were initially found to be useful reagents by Nobel Laureate H.C. Brown. Their precursors are commercially available and derivatization is fast, clean and simple.