Diagnostic Nuclear Medicine

Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

The gold standard text-reference Diagnostic Nuclear Medicine is now in its Fourth Edition--with a sharp clinical focus, a streamlined new single-volume format, and a very attractive price. Written by the top authorities in the specialty, this brand-new edition offers encyclopedic coverage of clinically relevant developments in nuclear medicine--including instrumentation, radiopharmaceuticals, and applications. Readers will find the latest on PET, molecular imaging, SPECT myocardial perfusion imaging, monoclonal antibody therapy, and the use of functional imaging studies in oncology. This edition has been trimmed from two volumes to one, so that readers can find exactly what they need quickly, without cross-checking between volumes.

​This work is devoted to understanding the recent advances in nuclear medicine and molecular imaging technologies along with their application to integrated medical therapy and future drug development. This anthology is based on the international symposium in 2015 entitled “Perspective on Nuclear Medicine for Molecular Diagnosis and Integrated Therapy. “The symposium provided an opportunity to exchange ideas on how to promote nuclear medicine technology and how to extend the technology to medical therapy and drug development, and was also a good opportunity to discuss the future perspective of nuclear medicine and molecular imaging by worldwide leaders in the field. Molecular imaging technologies have been rapidly developed worldwide in recent years. Among those developments, nuclear medicine has come to play an important role in quantitative analysis of biological process in vivo as well as in wide clinical use. With the current progress of nuclear medicine and molecular imaging, this modality has been applied for treatment monitoring and predicting its outcome with the use of optimal imaging biomarkers and suitable quantitative analysis. Truly, a new era has arrived with clinical use of nuclear medicine and molecular imaging for personalized medicine. This volume will benefit a wide variety of researchers in life science including those working in drug development, molecular imaging, and medical therapy as well as physicians who utilize diagnostic imaging.

A tactical guide for radiologists and nuclear medicine physicians, Diagnostic Imaging: Nuclear Medicine, Second Edition is practical, easy-to-use, and in-touch with the realities of multimodality diagnostic imaging. This comprehensive yet accessible reference addresses the most appropriate nuclear medicine options available to answer specific clinical questions within the framework of all imaging modalities. Sweeping updates include a complete reorganization, new differential diagnoses based on findings, and new chapters on physics and Nuclear Regulatory Commission guidelines. User-friendly bulleted text and a uniform chapter layout allow fast and effortless access to the crucial knowledge you need! Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, 2,000 full-color annotated images, and an extensive index Expanded coverage of the most important topics and trends in nuclear medicine including Recently revised radioactive iodine therapy guidelines for hyperthyroidism and thyroid cancer New bone tumor therapy radium-223 (currently indicated for treatment of painful bone metastases in prostate cancer) New I-123 ioflupane dopamine transporter imaging for diagnosis of parkinsonian syndromes F-18 PET/CT bone scan (particularly its indication for nonaccidental trauma in children) Meticulous updates throughout reflect the latest advances as well as all study guide topics listed for the new American Board of Radiology exam, including physics and Nuclear Regulatory Commission guidelines Expert Consult eBook version included with purchase allows you to search all of the text, figures, and references from the book on a variety of devices

This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and - crease in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G. de Hevesy, quantitative imaging has only recently emerged as a promising approach for diagnosis and therapy of many diseases. An effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine instrumentation and dual-modality imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. A brief overview of each chapter is provided below. Chapter 1 presents a general overview of nuclear medicine imaging physics and instrumentation including planar scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Nowadays, patients’ diagnosis and therapy is rarely done without the use of imaging technology. As such, imaging considerations are incorporated in almost every chapter of the book. The development of dual-modality - aging systems is an emerging research field, which is addressed in chapter 2.

Designed to present students and professionals with a comprehensive update of recent developments not found in other textbooks on the subject, the various clinical applications of nuclear medicine techniques are considered here, and due attention is also given to radiopharmaceuticals, equipment and instrumentation, reconstruction techniques and the principles of gene imaging