Embryo And Fetal Pathology

Uniquely authoritative and exhaustively illustrated in color, this atlas provides the clinician with a visual guide to diagnosing congenital anomalies in every organ system in the human fetus.

An illustrated textbook which describes the developmental pathology of the embryonic, foetal and perinatal periods. The first half of the book discusses such topics as normal development, concepts of embryo-foetal disease and dysmorphology, metabolic, infectious, neoplastic and placental disorders, and the pathology of abortions and multiple gestation. The second half focuses on systemic pathology. The book concludes by examining the autopsy of foetus and embryo and examination of the placenta.

This book is designed primarily for anatomic pathologists to facilitate their task of accurately diagnosing embryos and fetuses. A detailed examination of the products of spontaneous and induced abortions is necessary for accurate genetic counseling and for establishing the risk for specific abnormalities or another spontaneous pregnancy loss in the future. The growing interest in the defects of early development reflects the profound change in general life-style. In the past, spontaneous abortions were considered a common, usually sporadic event in a patient's reproductive history. Only reassurance and encour agement were given to the patient and scant attention was paid to the detailed pathology of the abortus. Nowadays, however, as a result of reliable methods of contraception and of the availability of reliable prenatal diagnosis for chromosome abnormalities more frequent in advanced maternal age, significant numbers of parents plan to have pregnan cies later in their reproductive life. Consequently, in a case of spontaneous abortion, the question of "cause" and of "future risk" of recurrence of abortion or an abnormal infant is particularly important. In the era of more elaborate and accurate prenatal diagnostic tests, the pathologist examining products of conception has a primary responsibility to detect, in both spontaneous and induced abortions, any developmental abnormality that would indicate an increased risk of multifactorial, chromosomal, and single gene disorders in a subsequent child.

Exhaustively illustrated in color with over 1000 slides, figures, and sonographs, this uniquely authoritative atlas provides the clinician with a visual guide to diagnosing congenital anomalies in every organ system in the human fetus. Gross pathologic findings are correlated with sonographic features to confirm visually the diagnoses for all organ systems. All practitioners of maternal-fetal medicine will find this atlas an invaluable resource.

This comprehensive reference addresses all aspects of fetal and neonatal pathology, including complicated pregnancies, multiple pregnancies, abortion, placental pathology, and disorders affecting the full-term neonate. A consistent organization allows for quick access to specific guidance, and nearly 2,500 illustrations - 2,350 in full color - depict conditions and abnormalities as they present in practice, facilitating diagnosis. An Image Bank on CD-ROM - new to this edition - features all of the illustrations from the 2-volume set, downloadable for presentations.

This comprehensive reference addresses all aspects of fetal and neonatal pathology, including complicated pregnancies, multiple pregnancies, abortion, placental pathology, and disorders affecting the full-term neonate. A consistent organization allows for quick access to specific guidance, and nearly 2,500 illustrations - 2,350 in full color - depict conditions and abnormalities as they present in practice, facilitating diagnosis. An Image Bank on CD-ROM - new to this edition - features all of the illustrations from the 2-volume set, downloadable for presentations. Offers comprehensive coverage of all common and rare embryonic, fetal, and infant disorders in one source. Correlates clinical, pathologic, and genetic findings for each systemic disease. Emphasizes the genetic and molecular basis of birth defects. Features nearly 2,500 illustrations - 2,350 in full color - which depict each abnormality or condition as they present in practice. Presents practical information on autopsy techniques and protocols. Provides the latest guidance on molecular pathology, immunohistochemistry, DNA technology, and more. Offers an expanded discussion of developmental biology related to the pathogenesis of birth defects. Features user-friendly summary tables and diagnostic flow charts, making information quick and easy to find. Includes a CD-ROM featuring all of the illustrations from the 2-volume set.

Describes and illustrates the range of pathological abnormality encountered, whether in spontaneous abortion or following termination for recognized foetal anomaly. A short, didactic account of foetal pathology which should be of interest to all surgical pathology departments.

This is a completely new, second edition of the classic reference which has been out of print since 1984. It is the most comprehensive work available on placental pathology, which has recently gained importance in clinical medicine, and includes discussion of legal aspects dealing with the relation between placenta and perinatal damage.