Engineering Of Biomaterials

This book focuses on biomaterials of different forms used for medical implants. The authors introduce the characteristics and properties of biomaterials and then dedicate special chapters to metallic, ceramic, polymeric and composite biomaterials. Case studies on sterilization methods by biomaterials are also presented. Finally, the authors describe the degradation and effects of biomaterials in living tissue.

A succinct introduction to the field of biomaterials engineering, packed with practical insights.

This book is written for those who would like to advance their knowledge beyond an introductory level of biomaterials or materials science and engineering. This requires one to understand more fully the science of materials, which is, of course, the foundation of biomaterials. The subject matter of this book may be divided into three parts: (1) fundamental structure-property relationships of man-made materials (Chapters 2-5) and natural biological materials, including biocompatibility (Chapters 6 and 7); (2) metallic, ceramic, and polymeric implant materials (Chapters 8-10); and (3) actual prostheses (Chapters 11 and 12). This manuscript was initially organized at Clemson University as classnotes for an introductory graduate course on biomaterials. Since then it has been revised and corrected many times based on experience with graduate students at Clemson and at Tulane University, where I taught for two years, 1981-1983, before joining the University of Iowa. I would like to thank the many people who helped me to finish this book; my son Y oon Ho, who typed all of the manuscript into the Apple Pie word processor; my former graduate students, M. Ackley Loony, W. Barb, D. N. Bingham, D. R. Clarke, J. P. Davies, M. F. DeMane, B. J. Kelly, K. W. Markgraf, N. N. Salman, W. J. Whatley, and S. o. Young; and my colleagues, Drs. W. Cooke, D. D. Moyle (Clemson G. H. Kenner (University of Utah), F. University), W. C. Van Buskirk (Tulane University), and Y.

The current interest in developing novel materials has motivated an increasing need for biological and medical studies in a variety of dinical applications. Indeed, it is dear that to achieve the requisite mechanical, chemical and biomedical properties, especially for new bioactive materials, it is necessary to develop novel synthesis routes. The tremendous success of materials science in developing new biomaterials and fostering technological innovation arises from its focus on interdisciplinary research and collaboration between materials and medical sciences. Materials scientists seek to relate one natural phenomenon to the basic structures of the materials and to recognize the causes and effects of the phenomena. In this way, they have developed explanations for the changing of the properties, the reactions of the materials to the environment, the interface behaviors between the artificial materials and human tissue, the time effects on the materials, and many other natural occurrences. By the same means, medical scientists have also studied the biological and medical effects of these materials, and generated the knowledge needed to produce useful medical devices. The concept of biomaterials is one of the most important ideas ever generated by the application of materials science to the medical field. In traditional materials research, interest focuses primarilyon the synthesis , structure, and mechanical properties of materials commonly used for structural purposes in industry, for instance in mechanical parts of machinery.

Written by an exceptionally experienced author in the area of medical equipment product design, this text presents a comprehensive overview of such sound principles and state-of-the-art techniques covering a whole host of material types, biocompatability, the design process and future trends within this exciting field. An all-in-one reference text, concise and easy-to-read. Wide audience appeal, from industry professionals to students of design.

Foundations of Biomaterials Engineering provides readers with an introduction to biomaterials engineering. With a strong focus on the essentials of materials science, the book also examines the physiological mechanisms of defense and repair, tissue engineering and the basics of biotechnology. An introductory section covers materials, their properties, processing and engineering methods. The second section, dedicated to Biomaterials and Biocompatibility, deals with issues related to the use and application of the various classes of materials in the biomedical field, particularly within the human body, the mechanisms underlying the physiological processes of defense and repair, and the phenomenology of the interaction between the biological environment and biomaterials. The last part of the book addresses two areas of growing importance: Tissue Engineering and Biotechnology. This book is a valuable resource for researchers, students and all those looking for a comprehensive and concise introduction to biomaterials engineering. Offers a one-stop source for information on the essentials of biomaterials and engineering Useful as an introduction or advanced reference on recent advances in the biomaterials field Developed by experienced international authors, incorporating feedback and input from existing customers

Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field. Provides a self-contained work for the field of biomaterials for drug delivery Summarizes the current knowledge on PEGylation and strategies for bypassing it Presents research on an important, though under-represented issue in biomaterials Written by a world-class team of research scientists, engineers and clinicians

This book presents a broad scope of the field of biomaterials science and technology, focusing on theory, advances and applications. It is written for those who would like to develop their interest and knowledge towards biomaterials or materials science and engineering. All aspects of biomaterials science are thoroughly addressed, from basic principles of biomaterials, organs and medical devices to advanced topics such as tissue engineering, surface engineering, sterilization techniques, 3D printing and drug delivery systems. Readers are also introduced to major concepts of surface modification techniques, and potential applications of different classes of biomaterials. Multiple-choice questions at the end of every chapter will be helpful for students to test their understanding of each topic, with answers provided at the end of the book.Ultimately, this book offers a one-stop source of information on the essentials of biomaterials and engineering. It is useful both as an introduction and advanced reference on recent advances in the biomaterials field. Suitable readers include undergraduate and graduate students, especially those in Materials Science, Biomedical Engineering and Bioengineering.