Molecular Aspects Of Anticancer Drug Dna Interaction
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Molecular Aspects of Anticancer Drug DNA Interactions
Author | : Stephen Neidle |
Publsiher | : CRC Press |
Total Pages | : 386 |
Release | : 1994-05-03 |
Genre | : Medical |
ISBN | : 0849377730 |
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This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that could be crucial for the discovery of new therapeutic substances. It is an important reference for molecular biologists, cancer researchers, biochemists, biophysicists, and pharmacologists.
Molecular Aspects of Anticancer Drug DNA Interaction
Author | : Neidle |
Publsiher | : CRC Press |
Total Pages | : 394 |
Release | : 1993-08-16 |
Genre | : Medical |
ISBN | : 0849377706 |
Download Molecular Aspects of Anticancer Drug DNA Interaction Book in PDF, Epub and Kindle
This cutting-edge book surveys the current knowledge on the mode of action of the major classes of DNA-interactive antitumor agents, providing information that could be crucial for the discovery of new therapeutic substances. It is an important reference for molecular biologists, cancer researchers, biochemists, biophysicists, and pharmacologists.
Molecular Aspects of Anticancer Drug DNA Interactions c1994
Author | : Stephen Neidle,Michael J. Waring |
Publsiher | : Unknown |
Total Pages | : 0 |
Release | : 1993 |
Genre | : Antimitotic agents |
ISBN | : 033355115X |
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Molecular Aspects of Anti cancer Drug Action
Author | : Stephen Neidle,Michael J. Waring |
Publsiher | : Verlag Chemie |
Total Pages | : 424 |
Release | : 1983 |
Genre | : Medical |
ISBN | : UOM:39015009541288 |
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Drug DNA Interaction Protocols
Author | : Keith R. Fox |
Publsiher | : Springer Science & Business Media |
Total Pages | : 296 |
Release | : 1997-10-07 |
Genre | : Medical |
ISBN | : UOM:39015040372446 |
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A collection of useful molecular techniques to illuminate and explore the interaction of drugs and ligands with DNA. These easily reproducible methods involve sequence recognition properties, as well as the physical approaches for measuring both the strength of interaction and the mode of drug binding to DNA. The interactions are also examined from a cellular perspective and for their usefulness in the design of new therapeutic agents. The powerful techniques detailed here will be particularly useful in elucidating the action of existing therapeutic agents, as well as in the design of new anti-cancer drugs with improved action and reduced toxicity.
Advances in DNA Sequence specific Agents
Author | : J.B. Chaires |
Publsiher | : Elsevier |
Total Pages | : 246 |
Release | : 1996-07-09 |
Genre | : Science |
ISBN | : 0080526144 |
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DNA sequence specificity is a sub-specialty in the general area of molecular recognition. This area includes macromolecular-molecular interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter group of DNA sequence specificity interactions that is the subject of Volumes 1 and 2 of Advances in DNA Sequence Specific Agents. As was the case for Volume 1, Part A also covers methodology, but in Volume 2 we include calorimetric titrations, molecular modeling, X-ray crystallographic and NMR structural studies, and transcriptional assays. Part B also follows the same format as Volume 1 and describes the sequence specificities and covalent and noncovalent interactions of small ligands with DNA. This volume is aimed in general at scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. The methods have general applicability to small molecules as well as oligomers and proteins, while the examples provide general principles involved in sequence recognition.
Metallopharmaceuticals I
Author | : Michael J. Clarke,Peter J. Sadler |
Publsiher | : Springer Science & Business Media |
Total Pages | : 218 |
Release | : 1999-05-21 |
Genre | : Science |
ISBN | : 3540648895 |
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Each volume provides the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, with a comprehensive summary and critical overview of a topic of great current interest written by leading international experts.
Drug DNA Interactions
Author | : Kazuo Nakamoto,Masamichi Tsuboi,Gary D. Strahan |
Publsiher | : John Wiley & Sons |
Total Pages | : 475 |
Release | : 2008-09-08 |
Genre | : Science |
ISBN | : 9780470369166 |
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Learn vital information about drug-DNA interactions from Drug-DNA Interactions: Structures and Spectra, the only comprehensive book written about this topic. Understand the types of structural and bonding information that can be obtained using specific physico-chemical methods and discover how to design new drugs that are more effective than current treatments and have fewer side effects. Find detailed information about X-ray crystallography, NMR spectroscopy, molecular modeling, and optical spectroscopy such as UV-Visible absorption, fluorescence, circular dichroism (CD), flow linear dichroism (FLD), infrared (IR) and Raman spectroscopy.