Osseoconductive Surface Engineering For Orthopedic Implants

Osseoconductive Surface Engineering for Orthopedic Implants provides a comprehensive overview of the state of the art of osseointegration based on surface-mediated engineering. It offers a practical approach to the design and development of implant surface engineering, by reviewing and discussing the usability and efficacy of each processing technique. The reader can learn about the variety, characteristics, advantages, challenges, and optimum parameters for each process—enabling targeted selection of coatings and technologies to enhance long-term implant–bone integration. Practical and engineering notions in the field of osseoconductive surface engineering are reviewed and discussed using scientific principles and concepts. Engineering cases are analyzed in depth giving a thorough exploration and description of the engineering and scientific concepts for all osseoconductive surface engineering processes. Chapters integrate topics and are organised in such a way as to build on themes and practice.

Osseointegration of Orthopaedic Implants helps product developers at orthopedic implant manufacturers enhance the effectiveness of orthopedic implants and reduce complications, particularly in patients with osteoporotic bones. The book's expert contributors provide cutting-edge information on the latest technologies and advances available. Biomaterial researchers can use the book for basic data in the further development of orthopedic implant materials with better osseointegration. Biomechanical researchers can review related challenges and concepts of osseointegration for use in the development of implants. The book is suitable for readers from academia and industry, bridging the knowledge gap between academic based researchers, industrial based engineers, and clinical based surgeons. Reviews and discusses all aspects of orthopedic implant osseointegration Provides conceptual implants for bone fracture fixation and joint replacement Offers novel ideas for the development of orthopedic implants with superior osseointegration

Interactions of Bone with Orthopedic Implants and Possible Failures focuses on the mechanical and biological issues that may cause failure of the implant-bone construct. The book provides discussions on the effects of the design, process, surface and other engineering parameters of implants and their interaction with bone tissue. For implant designers, it is highly crucial to know the final effects of what they are designing or aiming to design, along with performance parameters. It is also crucial for orthopedic surgeons to be familiar with the background of the design and process parameters of the implant they will insert in a patient’s body. With the understanding brought forth in this book, surgeons can have better implant options and implant designers can create and develop new implant designs. This book can also help biomechanical and mechanical engineers who are normally dealing with testing and analysis of orthopedic implants examine the biomechanical behavior of the implants and their interaction with bone tissue. Explains interactions, along with possible complications of trauma, joint and spinal implants, and failures of the implant and bone tissue Focuses on issues such as bone loss, defects and resorption at the bone and implant interface Includes case studies of implant failures and discusses the mechanical and biological reasons that would cause failure of bone and implant integration

This new book synthesizes a wide range of interdisciplinary literature to provide the state-of-the art of biomedical implants. It discusses materials and explains the three basic requirements for implant success from a surface engineering perspective: biological compatibility, biomechanical compatibility, morphological compatibility. Biomedical, mechanical, and materials engineers will find this book indispensable for understanding proper treatment of implant surfaces in order to achieve clinical success. Highlights include: • Coverage of surface engineering of polymer, metallic, ceramic and composite implant materials; • Coverage of chemical, mechanical, physical, thermal, and combined surface modification technologies; • Explanations of interfacial reaction between vital tissue and non-vital implant surface; and • Methodologies and technologies for modification of surface layer/zone to promote the osteo-integration, the ultimate success for biomedical implants in both dental and medical practice.

This book covers the latest progress in the biology and manufacturing of orthopedic biomaterials, as well as key industry perspectives. Topics covered include the development of biomaterial-based medical products for orthopedic applications, anti-infection technologies for orthopedic implants, additive manufacturing of orthopedic implants, and more. This is an ideal book for graduate students, researchers and professionals working with orthopedic biomaterials and tissue engineering. This book also: Provides an industry perspective on technologies to prevent orthopedic implant related infection Thoroughly covers how to modulate innate inflammatory reactions in the application of orthopedic biomaterials Details the state-of-the-art research on 3D printed porous bone constructs

Total joint arthroplasty is an effective surgical procedure for end-stage osteoarthritis of major joints with satisfactory long term clinical outcome. A large and growing number of arthroplasties are performed annually worldwide and a great number of orthopaedic surgeons are practicing arthroplasty surgery as their main surgical activity. The biological behavior of the bone-implant interface is crucial for the long term survival of the artificial joint. All factors which have a positive or negative effect on the interface are of great interest for those practicing arthroplasty surgery. Basic scientists and the industry are continuously searching for new implant fixation mechanisms and improved materials. There is an accumulation of a great amount of basic science data (both biological, material and mechanical) related to the incorporation or loosening of the bone-implant interface. However, basic science data does not always translate to satisfactory clinical application, and orthopaedic practitioners often wonder which piece of information is clinically useful. A further problem is that basic scientists often speak their own scientific language and may not fully appreciate common clinical practice needs. In this textbook the biological and mechanical mechanisms of implant incorporation and loosening will be presented. All new data concerning materials and methods for incorporation enhancement will be critically analyzed. Data useful for clinical application will be stressed. Orthopaedic Surgeons will find information which will improve their clinical practice and basic scientists will be helped to understand and appreciate clinical needs.

Bone Response to Dental Implant Materials examines the oral environment and the challenges associated with dental biomaterials. Understanding different in vivo and in vitro responses is essential for engineers to successfully design and tailor implant materials which will withstand the different challenges of this unique environment. This comprehensive book reviews the fundamentals of bone responses in a variety of implant materials and presents strategies to tailor and control them. Presents a specific focus on the development and use of biomaterials in the oral environment Discusses the basic science of the dental interface and its clinical applications Contains important coverage on the monitoring and analysis of the dental implant interface

Proceedings of the NATO Advanced Study Institute on `Materials Science and Orthopaedic Surgery II', Chania, Crete, Greece, June 19--July 2, 1994