Parasites And Pathogens

When Nancy Beckage and I first met in Lynn Riddiford's laboratory at the University of Washington in the mid 1970s, the fields of parasitology, behavior, and endocrinology were thriving and far-flung--disciplines in no serious danger of intersecting. There were rumors that they might have some common ground: Behavioural Aspects of Parasite Transmission (Canning and Wright, 1972) had just emerged, with exciting news not only of the way parasites themselves behave, but also of Machiavellian worms that caused intermediate hosts to shift fundamental responses to light and disturbance, becoming in the process more vulnerable to predation by the next host (Holmes and Bethel, 1972). Meanwhile, biologists such as Miriam Rothschild (see Dedication), G. B. Solomon (1969), and Lynn Riddiford herself (1975) had suggested that the endocrinological rami of parasitism might be subtle and pervasive. In general, however, para fications sites were viewed as aberrant organisms, perhaps good for a few just-so stories prior to turning our attention once again to real animals. In the decade that followed, Pauline Lawrence (1986a,b), Davy Jones (Jones et al. , 1986), Nancy Beckage (Beckage, 1985; Beckage and Templeton, 1986), and others, including many in this volume, left no doubt that the host-parasite combination in insect systems was physiologically distinct from its unparasitized counterpart in ways that went beyond gross pathology.

Both volumes of Parasites and Pathogens of Insects provide in-depth coverage of the interface between insect parasites and pathogens and hosts, and explore the relationships between these partners. They emphasize biochemical and molecular interactions, basic biology, and the roles of hormones, receptors, and other cellular components in modulating interactions between host insects and attacking agents. These topics also are assessed in relation to biotechnology and biological control. In the short term, these volumes fill a void in current literature by emphasizing basic interactions at the biochemical and molecular levels. In the long term, these interactions may provide avenues for exploitation to enhance the rate of "beneficial" parasitism or to reduce the rates of disease transmission and infection of vertebrate hosts. Presents the latest information on insect parasites and pathogens Describes biochemical and molecular host-parasite and host-pathogen relationships Covers mechanisms of insect pathogenicity and resistance Provides exceptional breadth of coverage and authoritative reviews Special topics Transposable elements in insect pathogens Co-evolution and gene transfer between hosts and invaders Biological control

Traditionally, laboratory identification of parasites has relied upon various phenotypic procedures that detect their morphological, biological, and immunological features. Because these procedures tend to be time-consuming and technically demanding, molecular methods based on nucleic acid amplification technologies have been increasingly utilized

After the publication of the Diagnostic Manual for the Identification of Insect Pathogens, the authors received many queries asking why they had not included the larger metazoan parasites as well as the microbial forms. An examination of the literature indicated that pictorial guides to the identification of nematodes and the immature stages of insect parasites were unavailable. Consequently we decided to rewrite the sections cover ing insect pathogens and combine these with new sections on ento mogenous nematodes and the immature stages of insect parasites. The result is the present laboratory guide, which is unique in covering all types of biotic agents which are found inside insects and cause them injury or disease. Included as parasites are insects and nematodes. Among the pathogens included are viruses, rickettsias, bacteria, fungi, and protozoans. Emphasis is placed on identification with an attempt to use the most easily recognizable characters. Use of a certain number of technical terms is unavoidable, and explanations of these can be found in most biological dictionaries or the glossary of invertebrate pathology prepared by Steinhaus and Martignoni (1970).

This book examines the two major parasite groups that are transmitted via water or foods: the single-celled protozoa, and the helminths: cestodes (tapeworms), nematodes (round worms), and trematodes (flukes). Each chapter covers the biology, mechanisms of pathogenesis, epidemiology, treatment, and inactivation of these parasites. This important new text offers a better understanding of the biology and control of parasitic infections necessary to reduce or eliminate future outbreaks in the U.S. and elsewhere.

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

The crucial role played by diseases in economic progress, the growth of civilizations, and American history. In Parasites, Pathogens, and Progress, Robert McGuire and Philip Coelho integrate biological and economic perspectives into an explanation of the historical development of humanity and the economy, paying particular attention to the American experience, its history and development. In their path-breaking examination of the impact of population growth and parasitic diseases, they contend that interpretations of history that minimize or ignore the physical environment are incomplete or wrong. The authors emphasize the paradoxical impact of population growth and density on progress. An increased population leads to increased market size, specialization, productivity, and living standards. Simultaneously, increased population density can provide an ecological niche for pathogens and parasites that prey upon humanity, increasing morbidity and mortality. The tension between diseases and progress continues, with progress dominant since the late 1800s. Integral to their story are the differential effects of diseases on different ethnic (racial) groups. McGuire and Coelho show that the Europeanization of the Americas, for example, was caused by Old World diseases unwittingly brought to the New World, not by superior technology and weaponry. The decimation of Native Americans by pathogens vastly exceeded that caused by war and human predation. The authors combine biological and economic analyses to explain the concentration of African slaves in the American South. African labor was more profitable in the South because Africans' evolutionary heritage enabled them to resist the diseases that became established there; conversely, Africans' ancestral heritage made them susceptible to northern “cold-weather” diseases. European disease resistance and susceptibilities were the opposite regionally. Differential regional disease ecologies thus led to a heritage of racial slavery and racism.