Prostate Cancer New Profiles New Challenges

Prostate cancer continues to be a major threat to men's health, thesecond most common cancer in men, in many countries. Therefore itis increasingly important that those faced with difficult clinicalquestions make the right decisions. Since the first volume waspublished in 2000, many debates persist but new controversies havealso emerged, reflected in the chapters of this new volume. Newauthors have been recruited to give their insight into newer areasof this controversial topic. Challenges in prostate cancer provides a series ofstate-of-the-art review articles, each of which addresses andanswers a contentious question. It includes chapters on medical andsurgical management of all stages of prostate cancer, clinicalinvestigation, epidemiology, clinical trials and basic scientificresearch and covers issues such as the genetic basis of cancer,clinical economics and influence. The authors have used their expertise to distil the availableevidence into practical advice to be used by busy urologists intheir day-to-day practice. And as well as being an overview ofcurrent practice many chapters attempt to give insights into thefuture direction of prostate cancer research and clinicalmanagement.

Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers. The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth. Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.

This fully updated and revised new edition provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in prostate cancer. The book reviews new data about molecular characteristics of the disease, profiles the new grading system for prostate cancer introduced in 2015, and provides new perspectives about imaging of prostate cancer, as well as the role of targeted biopsies. The text summarizes the role of biomarkers and MRI in patient selection and management and details the world wide results of active surveillance. Specific chapters address communication and ethical issues, QOL outcomes, economic aspects, and psycho-social aspects of surveillance. The role of focal therapy for low risk disease is summarized, and the data supporting preventive interventions during surveillance reviewed. This text will serve as a very useful resource for physicians and researchers dealing with, and interested in this common malignancy, as it provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.

Men who have completed prostate cancer treatment often find themselves facing new challenges and setbacks that do not necessarily recede along with the cancer. Many books endeavor to explain the different types of prostate cancer treatments, but most conclude once a treatment choice has been made, offering readers little in the way of guidance through the challenges of the post-treatment period. After Prostate Cancer: A What-Comes-Next Guide to a Safe and Informed Recovery picks up where those books leave off. Dr. Arnold Melman, Chair of the Department of Urology at the Albert Einstein College of Medicine, offers a thorough description of what the prostate cancer recovery process is like and what readers can do to move themselves through recovery to the best possible health and long-term prognosis. Giving detailed explanations of what to expect and why based on diagnosis, treatment methodology, and other variables that make each man's post-treatment experience different, Dr. Melman offers strategies for mindfully and healthfully approaching post therapy issues, including confronting PSA measurement, erectile dysfunction, urinary incontinence and psychological issues that are a common result of living through prostate cancer and treatment. Sharing the experiences of other prostate cancer patients in addition to accessible explanations of the available medical literature, Dr. Melman helps readers and their partners to get the best information, make the most informed decisions, feel comfortable with those decisions, and work through issues as they arise. Treatment is only the beginning of getting back to a healthy life after a diagnosis. After Prostate Cancer offers the best information to help readers with everything that comes next. "After Prostate Cancer offers readers order who are often faced with chaos. Melman and Newnham have written an informative guide for the recovering prostate cancer patient."--Mani Menon, M.D., The Raj and Padma Vattikuti Distinguished Chair and Director, Vattikuti Urology Institute, Henry Ford Health System "Now the hundreds of men who have benefitted directly from Dr. Arnold Melman's compassionate care for prostate cancer will swell into the thousands as the readers of this book take home his wisdom and sound advice. The information he provides is straightforward and practical, including both medical and emotional sides of the experience. This book is a welcome addition to the self-help library for prostate cancer survivors."--Leslie R. Schover, Ph.D., Professor of Behavioral Science, University of Texas MD Anderson Cancer Center "This book summarizes the field of recovery after prostate cancer perfectly for the patient and his family. The authors cover all the topics that patients who have undergone treatment want to know about, including how to manage side effects. The text is readable and the information is imparted in an easy-to-understand style. I recommend this book to patients, their loved ones, and anyone else who has been affected by a prostate cancer diagnosis."--Ashutosh K. Tewari, M.D., M.Ch., Director, Prostate Cancer Institute and the LeFrak Robotic Surgery Center, Weill Cornell Medical College

In recent years the pace of research in prostate cancer has increased dramatically. Creative ideas in combination with new and emerging technologies have led to an explosion of discovery. These types of advances in prostate cancer research presage an era of new treatment strategies based on an understanding of the cellular and molecular mechanisms of disease. In creating this book, we aimed to cover a broad "bench to bedside" research spectrum ranging from: genetic, molecular and cellular analyses to epidemiological studies, refinements in local treatment strategies and new biologically based non-hormonal treatments for systemic disease. Researchers and clinicians will find in this book a group of timely and clinically relevant chapters on prostate cancer research and treatment.

Prostate Cancer: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Prostate Cancer: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Prostate Cancer: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.