Wounds That Will Not Heal

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Designed for health care professionals in multiple disciplines and clinical settings, this comprehensive, evidence-based wound care text provides basic and advanced information on wound healing and therapies and emphasizes clinical decision-making. The text integrates the latest scientific findings with principles of good wound care and provides a complete set of current, evidence-based practices. This edition features a new chapter on wound pain management and a chapter showing how to use negative pressure therapy on many types of hard-to-heal wounds. Technological advances covered include ultrasound for wound debridement, laser treatments, and a single-patient-use disposable device for delivering pulsed radio frequency.

Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds. Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices. With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject. Provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds Chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing Covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair

Despite enormous advances made in the development of external effector prosthetics over the last quarter century, significant questions remain, especially those concerning signal degradation that occurs with chronically implanted neuroelectrodes. Offering contributions from pioneering researchers in neuroprosthetics and tissue repair, Indwelling Neural Implants: Strategies for Contending with the In Vivo Environment examines many of these challenges, paying particular attention to how the healing of tissues surrounding an implant can impact the intended use of a device. The contributions are divided into four sections · Part one examines wound healing from the initial insertion trauma through the inflammatory and repair process, explaining how the action of healing varies throughout different areas of the body. · Part two considers various performance issues specific to particular implant components, including those that arise from the chemical, mechanical, thermal, and electrical impact on surrounding tissues. It discusses challenges that result from chronic tissue stimulation and heat effects that occur with on-chip and telemetric processing. · Part three presents both in vitro and in vivo approaches to assessing wound healing response to materials. It includes the contribution of the developer of a chronic hollow fiber membrane implant who explains how an in vivo model is used to assess molecular transport in brain tissue surrounding the implant. · The final section evaluates molecular and materials strategies for intervening in CNS wound repair and enhancing the electrical communication between the electrode surface and the surrounding tissue. It also presents novel approaches to nerve regeneration and repair. This seminal work provides researchers with an up-to-date account of the progress in the field that they can build upon to bring us closer to realizing the full value of neural implants in combating otherwise intractable human health problems.

Primary knee arthroplasty (PKA) has a long history and modern mobile bearing knee implants are successfully implanted worldwide since 1977. Primary Knee Arthroplasty focuses on basic science, personal surgical experiences, clinical, functional and radiographic outcomes of PKA, with special focus on challenging knees such as severe varus and valgus deformities with associated bone defects, fixed flexion deformities, soft tissue contractures, and arthrodesed knees. Patella treatment with or without resurfacing is addressed in great detail. Early criterion-based rehabilitation and the patient’s return to participating in sports are discussed as is the management of prosthetic or surgery related complications. Lavishly illustrated to complement the text, Primary Knee Arthroplasty is a ‘must-have’ for all practicing knee replacement surgeons, orthopedic surgeons in training, orthopedic nurses, and physiotherapists with a special interest in knee arthroplasty. Tips and tricks provided by experienced knee surgeons are indispensable for daily clinical practice.

Rev. ed. of: Acute and chronic wounds / [edited by] Ruth A. Bryant, Denise P. Nix. 3rd ed. c2007.

The ability of foetal tissue to heal without scarring is now well documented, but the potentially far-reaching implications of this process for the practice of surgery and the management of healing are just beginning to be understood. This book provides up-to-date information on the subject.

Alexis White spent much of her youth going after what she wanted and not caring who she hurt. She didn't care about Christopher's wife when she pursued an affair with him, but years later, she can admit that she was also wounded in the process. She's still dealing with the anguish of having aborted Christopher's baby and then losing the one man she believes ever loved her fully. In spite of her pain, Alexis realizes life must go on. More than a decade later, she has a successful pediatrics practice and is engaged to Jamar Duplessis. They have survived Hurricane Katrina, but with Hurricane Gustav threatening to strike, Alexis and Jamar must pack up and flee New Orleans. Unfortunately, Alexis finds herself right in the eye of another storm when she and Jamar decide to wait out the hurricane in Virginia Beach. Christopher and his wife Andrea live there, and are still nursing the wounds that Alexis helped to cause. Although Jamar is determined not to let this potential drama stress out his fiancée, an unexpected glitch in his finances demands his attention and nearly drives a wedge between him and Alexis. Someone is definitely out for revenge, but who? Is it Andrea? Christopher? Or maybe it's Alexis's former archrival, Nikki, who also makes a surprise appearance in Virginia Beach. Will Alexis be able to face the demons she thought she'd slayed years ago? This is a story of family, friendship, and forgiveness that proves that while time passes, some wounds never heal.