Uterine Pathology

Part of the Cambridge Illustrated Surgical Pathology series, this book provides a comprehensive account of the experienced gynecologic pathologists' diagnostic approach to uterine pathology. Discussion is built around major pathologic entities in the uterus and cervix while highlighting the diverse and complex spectrum of alterations encountered in daily practice. Emphasizing clear description, diagnostic algorithms and problem solving, the book's primary goal is to lay the foundation for diagnostic accuracy, reproducibility, and relevance. It also dispels common misconceptions and encourages an intelligent and thoughtful approach to diagnostic problems using all the tools available to the modern physician. The book is richly illustrated, with more than 700 color photomicrographs, all of which are also found in downloadable format on the accompanying CD-ROM.

Changing approaches to diagnosis and clinical management of the uterus are comprehensively examined in this book. It gives a concise update of new concepts in physiology and pathology and their application in clinical practice. The book is designed especially for the gynecologist actively involved in patient care. Topics discussed include the pathophysiology of diethylstilbestrol (DES) changes, the immunology of the uterus, papillomaviruses and cervical neoplasia, endocervical carcinoma, mesenchymal tumors and diagnostic procedures such as colposcopy of the cervix, hysterosalpingography, and magnetic resonance imaging. The status of contemporary management is presented for hysteroscopy and hysteroscopic surgery, the congenital absence of the uterus and vagina, anovulatory dysfunctional uterine bleeding of the adolescent, uterine leiomyomata, genital prolapse, endometrial adenocarcinoma and childhood rhabdomyosarcoma of the vagina and uterus.

This Atlas of Uterine Pathology is comprehensive overview of the major pathologic processes that may be encountered in the uterine corpus and cervix. Each section is lavishly illustrated and covers normal histology as well as neoplastic and non-neoplastic diseases. Emphasis is placed on presenting the full morphologic and immunophenotypic spectrum of entities, including classical and variant pathology, in a manner that maximizes the utility of the information in routine diagnostic practice.

Endometrial cancer remains the most frequent gynaecological cancer in first world countries.This bench book on endometrial pathology distils the current literature to provide a practical text on endometrial pathology. Differential diagnosis is emphasised, and the clinical correlates of pathology are also stressed to make this a clinically useful book.Fully updated and including over 400 colour images, this book provides a valuable resource for the practising pathologist in general and community hospitals as well as in teaching hospitals.

Endometrial Pathology is a practical, clinically oriented reference on endometrial pathology. It is detailed enough for pathologists yet has a clinical focus that ensures its relevance and appeal to gynaecologists. The book covers the clinical aspects of evaluating the endometrium and the pathology of endometrial diseases, with differential diagnoses included as appropriate. There is a chapter on the histologic pitfalls in diagnosis and a final chapter on the latest information on molecular mechanisms and immunohistochemical tests.

Hormonal influences, both natural and iatrogenic, are implicated in the most frequent health issues of women. Endometrial cancer is now the most common gynecologic cancer in the United States and the industrialized world. This cancer is strongly related to hormonal and metabolic factors. In addition, breast cancer treated with hormone therapy (Tamoxifen) may, in some cases, be associated with uterine pathology. Hormone therapy is used to improve the physiological effects and counteract abnormal and deleterious effects of “natural” hormonal activity. Millions of women receive hormone therapy at some point of their life: using oral contraceptives, reproductive technology, treatment for post-menopausal symptoms, among other uses. This book addresses a range of women’s health issues, from fertility to neoplasms, and their relationship with natural and iatrogenic hormonal effects. Chapters include clinical and pathological descriptions, theoretical and practical medical issues, and original studies and cases. Controversial issues in certain hormone therapies are presented with updated concepts based on clinical studies and novel statistical methods. The book will be useful for specialized and general physicians, oncologists, endocrinologists, researchers, medical students, and others in the field of women’s health.